Michael E Selsted Selected Research

Defensins

11/2019	Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms.
1/2018	Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme.
1/2017	Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.
7/2015	θ-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats.
1/2015	Microbicidal effects of α- and θ-defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa.
1/2014	Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions.
8/2012	θ-Defensins: cyclic peptides with endless potential.
3/2012	Alternative luminal activation mechanisms for paneth cell α-defensins.
3/2010	Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms.

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Michael E Selsted Research Topics

Disease

13	Infections 12/2021 - 09/2003
3	Sepsis (Septicemia) 12/2021 - 01/2012
3	Lung Diseases (Lung Disease) 08/2021 - 11/2009
3	Inflammation (Inflammations) 01/2018 - 01/2017
2	Severe Acute Respiratory Syndrome 01/2022 - 11/2009
2	Acute Lung Injury 01/2022 - 01/2018
2	Arthritis (Polyarthritis) 12/2019 - 01/2017
2	Rheumatoid Arthritis 12/2019 - 01/2017
2	Cystic Fibrosis (Mucoviscidosis) 01/2016 - 05/2002
1	COVID-19 01/2022
1	Gram-Negative Bacterial Infections 12/2021
1	Septic Shock (Toxic Shock Syndrome) 12/2021
1	Fever (Fevers) 08/2021
1	Invasive Fungal Infections 10/2020
1	Mycoses (Diseases, Fungus) 10/2020
1	Systemic candidiasis 11/2019
1	Candidiasis (Moniliasis) 11/2019
1	Pneumonia (Pneumonitis) 01/2018
1	Pulmonary Edema 01/2018
1	Lung Injury 01/2018
1	Joint Diseases (Joint Disease) 01/2017
1	Virus Diseases (Viral Diseases) 12/2015
1	Obesity 07/2015
1	Insulin Resistance 07/2015
1	Body Weight (Weight, Body) 07/2015
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2015
1	Type 2 Diabetes Mellitus (MODY) 07/2015
1	Peritonitis 01/2012
1	Wounds and Injuries (Trauma) 12/2002

Drug/Important Bio-Agent (IBA)

12	Peptides (Polypeptides)IBA 12/2021 - 05/2002
11	rhesus-theta-defensin-1IBA 01/2022 - 03/2010
9	DefensinsIBA 11/2019 - 03/2010
5	theta-defensinIBA 12/2021 - 10/2004
4	CytokinesIBA 12/2021 - 01/2012
3	Pharmaceutical PreparationsIBA 12/2021 - 11/2019
2	EndotoxinsIBA 01/2022 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 08/2021 - 09/2003
2	pristane (pristan)IBA 12/2019 - 01/2017
2	Anti-Infective Agents (Microbicides)IBA 12/2015 - 01/2015
2	Antimicrobial PeptidesIBA 11/2009 - 10/2004
1	Carbapenems (Carbapenem Antibiotics)IBA 12/2021
1	InflammasomesIBA 08/2021
1	NLR ProteinsIBA 08/2021
1	InterleukinsIBA 08/2021
1	PolyenesIBA 10/2020
1	AzolesIBA 10/2020
1	EchinocandinsIBA 10/2020
1	Antimicrobial Cationic PeptidesIBA 12/2019
1	ChemokinesIBA 01/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 07/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2015
1	Complementary DNA (cDNA)IBA 03/2010
1	human neutrophil peptide 1IBA 03/2010
1	Antiviral Agents (Antivirals)IBA 11/2009
1	beta-DefensinsIBA 10/2004
1	alpha-DefensinsIBA 09/2003
1	Inflammation MediatorsIBA 12/2002
1	cryptdin 3IBA 05/2002
1	cryptdinIBA 05/2002

Therapy/Procedure

1	Punctures 01/2012
1	Ligation 01/2012